在腹腔镜主要胃肠道手术中,氧化与苏芬坦尼尔结合四度腰部阻断与横腹部平面阻断:一个随机因子试验协议
Guo-Wang Yang1,2, Min-Yuan Zhuang1,2, Hai-Jing Shi1,2
1Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.
这项研究比较了 oxycodone 和 sufentanil 患者控制的止痛与四度腰部阻断和横向腹部平面阻断,以增强胃肠道手术后的恢复.
科学领域:
- 麻醉学 麻醉学
- 术后恢复 术后恢复
- 疼痛管理 疼痛管理
背景情况:
- 多模式止痛对于手术后更好的康复至关重要.
- laparoscopic胃肠道手术在疼痛管理和恢复方面提出了独特的挑战.
研究的目的:
- 研究不同止痛疗法对康复质量的影响.
- 为了比较基于氧化的与基于sufentanil的患者控制的止痛疗法.
- 为了评估四角腰部阻断与横向腹部平面阻断,结合止痛.
主要方法:
- 预期的,随机的,受控的临床试验,采用2x2的因数设计.
- 120名成年患者接受了腹腔镜主要胃肠道手术.
- 随机分配到四个组之一:氧化/QLB,氧化/TAPB,sufentanil/QLB,或sufentanil/TAPB.
主要成果:
- 主要结局:手术后24小时的康复质量 (QoR-15级).
- 二级结局:疼痛评分,止痛药消耗,不良事件和住院.
- 在多个时间点收集数据,直至手术后72小时.
结论:
- 该试验的目的是为最佳的多式模式止痛策略提供证据.
- 这些发现将指导临床实践,以改善腹腔镜胃肠道手术后患者的康复.
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