儿童时期的身体组成轨迹预测了青春期的骨成熟:一项纵向研究
Wen Shu1,2, Menglong Li3, Sten H Vermund4
1Department of Growth and Development, Capital Institute of Pediatrics, Beijing, 100020, China.
Heliyon
|September 10, 2024
概括
身体质量指数z-score和内脏脂肪区域z-score轨迹较高的儿童更有可能经历高级骨衰老. 保持正常的内脏脂肪区域是减少这种风险的关键.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 营养科学 营养科学
- 增长和发展 增长和发展
背景情况:
- 营养状况是线性骨生长的关键决定因素.
- 了解身体组成和骨成熟之间的联系对于儿科健康至关重要.
研究的目的:
- 为了研究身体组成轨迹与儿童骨晚年之间的关联.
- 为了确定特定的体质成分指标,预测青春期晚期骨年龄.
主要方法:
- 在一个儿科队列中,对体重指数z-score (BMI z-score),内脏脂肪区域z-score (VFA z-score),脂肪质量指数z-score (FMI z-score) 和无脂肪质量指数z-score (FFMI z-score) 的纵向分析.
- 在1402名小学生中使用坦纳 - 怀特豪斯三中半径 - 乌尔纳 - 短 (TW3-C RUS) 方法评估青春期骨龄.
- 统计分析以确定身体组成轨迹与骨晚年之间的关系.
主要成果:
- 较高的BMI z-score,VFA z-score,FMI z-score和FFMI z-score的轨迹与晚期骨衰老的可能性增加有关.
- 始终处于高VFAz分数组的儿童具有明显更高的骨老化风险 (OR = 6.73).
- 始终处于高BMIz-score组的儿童也有较高的骨衰老风险 (OR=5.57).
结论:
- 从童年开始追踪较高的体质成分指标,特别是内脏脂肪,会增加青春期骨老化发病的风险.
- 定期监测和管理儿童内脏脂肪区域可能有助于减轻骨晚年风险.
- 体重指数 (BMI) 监测是一种补充工具,尤其是在没有先进的身体成分评估工具的情况下.
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