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在HKU5冠状病毒中ACE2受体利用的融合演变的分子基础

Young-Jun Park1,2, Chen Liu3, Jimin Lee1

  • 1Department of Biochemistry, University of Washington; Seattle, WA 98195, USA.

bioRxiv : the preprint server for biology
|September 10, 2024
PubMed
概括

包括HKU5在内的Merbecoviruses可以使用ACE2受体进入细胞,而不仅仅是DPP4. 这一发现揭示了各种ACE2结合模式,并表明这种特征在冠状病毒中独立演变.

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