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A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM
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通过设计指导的质量开发隐蔽的Everolimus脂肪体配方:系统的优化和评估

Simranjeet Kaur1, Rajveer Singh2, Dilpreet Singh1

  • 1Department of Pharmaceutics, ISF College of Pharmacy, GT Road, Moga 142001, Punjab, India.

Current drug metabolism
|September 10, 2024
PubMed
概括

这项研究开发了一种新型隐形脂质体配方 (S-EVE-LIPO) 用于Everelimus (EVE),以提高生物可用性和减少副作用. 在临床前研究中,增强的配方证明了持续的药物释放和改善的治疗疗效.

关键词:
这是Everolimus.在MCF-7细胞系中.乳腺癌. 乳腺癌.细胞毒性 细胞毒性脂质体是一种脂质体.混合物设计 混合物设计

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