下降动力驱动器不会与肌肉代谢反射相互作用,以调节健康人体在节律性炼期间的通风
Felipe S Gomes1, Thiago R Lopes1,2,3, Richard M Bruce4
1Post-graduate Program in Translational Medicine, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
American journal of physiology. Lung cellular and molecular physiology
|September 10, 2024
概括
肌肉代谢反射和下降运动驱动器在运动期间不能协同调节肺通风. 这一发现表明,中央指挥和肌肉代谢反应之间的相互作用比以前理解的要复杂得多.
科学领域:
- 运动生理学 运动生理学
- 呼吸系统控制 呼吸系统控制
- 神经科学是一个神经科学.
背景情况:
- 肌肉代谢反射会影响运动期间的肺通风 (V̇E).
- 这种反射可能与中央命令相互作用,这是来自大脑的神经输出,驱动自愿运动.
- 了解这些相互作用对于理解运动诱导的呼吸暂停至关重要.
研究的目的:
- 为了研究下降动力驱动 (中央指挥的组成部分) 和肌肉代谢反射在V̇E调节之间的协同相互作用.
- 为了确定下降动力驱动是否调节节律性炼恢复期间对代谢反射激活的通风反应.
主要方法:
- 13名健康成年人进行了节奏握手运动,以激活肌肉代谢反射.
- 运动后的循环阻塞 (PECO) 在康复期间保持了代谢反射激活.
- 下降动力驱动是由自愿与非自愿的脚部曲操纵的.
- 肺透气 (V̇E) 在有或没有PECO的条件下以及随意或非自愿的腿部运动下进行测量.
主要成果:
- 握手运动在所有条件下同样增加了V̇E.
- 与恢复自由血流相比,PECO增加了V̇E.
- 自愿和非自愿的脚部曲引起了类似的V·E反应,不管PECO.
- 在V̇E的下降动力驱动和肌肉代谢反射之间没有观察到协同作用.
结论:
- 下降运动驱动器不会与肌肉代谢反应相互作用,以调节节律性炼恢复期间的肺通风.
- 中央指挥和肌肉代谢反射之间用于V̇E控制的拟议相互作用并不无处不在.
- 这些发现凸显了运动期间呼吸控制的复杂性.
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