肝移植后儿童的肉症:开发一个家庭视频程序来支持肌肉力量和功能-一项前后控制的试点研究
Amber Hager1, Normand Boule2, Lesley Pritchard3
1Department of Agricultural, Food & Nutritional Sciences, University of Alberta, Edmonton, Canada.
Clinical transplantation
|September 10, 2024
概括
抵抗训练 (RT) 对肝移植后的儿童来说是可行的和有效的,可以改善肌肉质量和身体性能. 这种干预措施可能有助于对抗这种人群中的肉症.
科学领域:
- 儿科移植 儿科移植
- 运动生理学 运动生理学
- 康复医学是康复的医学.
背景情况:
- 在肝移植 (LTx) 后的儿童中,肉类是普遍存在的担忧.
- 抵抗训练 (RT) 提出了一个潜在的治疗策略,以解决儿科LTx患者的肉症.
研究的目的:
- 评估一项为期12周的RT课程对LTx后儿童的可行性和影响.
- 评估骨肌肉质量 (SMM),肌肉力量和体力表现 (PP) 的变化.
- 探讨孩子和家长对参与RT的观点.
主要方法:
- 实施了使用电阻带的12周渐进式RT程序.
- 参与者包括6-18岁的儿童,无论是LTx后和健康对照 (HC).
- 测量包括通过MRI测量SMM和脂肪组织,肌肉强度测试和PP评估 (6分钟步行测试 [6MWT],定时上下楼梯测试 [TUDS]).
主要成果:
- 与HC相比,LTx儿童的腹部SM指数显著增加,内脏脂肪组织指数显著下降.
- 在LTx组中观察到6MWT距离,俯卧次数和TUDS完成时间的改善.
- 坚持和家庭参与积极影响了结果;较高的大腿肌肉脂肪含量与较差的PP相关.
结论:
- 抵抗训练是肝移植后儿童可行的和有效的干预措施.
- 在儿科LTx接受者中,RT可能会减轻与肉症相关的不良结果.
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