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Updated: Jun 19, 2026

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
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一个工程Nisin模拟器与一个疏水分子附在位置17选择性地抑制Enterococcus faecium菌株

Longcheng Guo1, Oscar P Kuipers1, Jaap Broos1

  • 1Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, 9747 AG, The Netherlands.

ACS chemical biology
|September 10, 2024
PubMed
概括

一种新的双作用抗生素,化合物47,是使用尼作为模板开发的. 这种修改后的兰蒂生物体对*E. faecium*具有增强的特异性,稳定性得到改善,并且保留了尼.

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