脑卒中后发作和增加了脑卒中幸存者中痴呆的风险:一个基于人口的研究
Kuan-Lin Sung1, Miao-Jen Kuo1, Hsin-Yi Yang2
1School of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Epilepsia
|September 10, 2024
概括
脑卒中后发作 (PSS) 或 (PSE) 在中风幸存者中显著增加痴呆的风险. 早期发作检测和治疗对于预防中风后痴呆症至关重要.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 全球老龄化人口面临中风和痴呆率上升的问题.
- 发作和是中风后的常见并发症,与随后的痴呆症发展密切相关.
研究的目的:
- 调查中风后发作 (PSS) 或中风后 (PSE) 与痴呆症发生率之间的关联.
- 用一个大型的国家医疗保健数据库来分析这种关系.
主要方法:
- 使用台湾国家医疗保险研究数据库 (2009-2020) 进行的回顾性队列研究.
- 确定的急性中风患者 (2010-2015年),不包括以前有神经疾病的患者.
- 根据年龄,性别,中风严重程度和指数中风年份,将PSS/PSE患者与没有中风的患者匹配.
主要成果:
- 包括62,968名患者 (平均年龄63岁,男性62.9%).
- 在5.2年的随访后,患有PSS/PSE的患者中,痴呆发病率为15.9%,而没有PSS/PSE的患者中为8.4%.
- 在所有类型,年龄,性别和严重程度的中风中,PSS/PSE与痴呆症有显著的相关性,在男性中更强烈的联系.
结论:
- 患有PSS或PSE的患者面临患痴呆症的风险更高.
- 针对发作和的治疗干预措施可以减少中风后痴呆症,突出了对中风幸存者的查和治疗的需要.
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