[血管化带:流行率和结构特征]
A N Stulova1, N S Semenova1, V S Akopyan1
1Lomonosov Moscow State University, Moscow, Russia.
Vestnik oftalmologii
|September 10, 2024
概括
在4.36%的眼睛中发现了斑点-状毛细血管 (MFC),在0.29%的眼睛中发现了先天性视网膜大血管 (CRM). 患有MFC的患者表现出更厚的内视网膜层和更浅的沟.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜成像 视网膜成像
- 血管生物学 血管生物学
背景情况:
- 形无血管区 (FAZ) 对于清晰的中央视力至关重要.
- 斑点内的血管异常,如斑点-状毛细血管 (MFC) 和先天性视网膜大血管 (CRM),可以影响视网膜结构和功能.
- 了解这些异常的患病率和结构影响对于诊断和管理视网膜疾病很重要.
研究的目的:
- 为了确定血管化叶区的流行率,特别是MFC和CRM.
- 分析MFC患者黄斑区域的结构特征.
主要方法:
- 使用光学一致性断层扫描血管学 (OCT-A) 评估MFC和CRM的患病率.
- 在MFC组和对照组之间对黄斑结构参数 (视网膜厚度,RNFL,GCL,IPL,INL,OPL,ONL,孔深度) 的比较分析.
主要成果:
- MFC的患病率为4.36% (45/1031只眼睛),而CRM的患病率为0.29% (3/1031只眼睛).
- 患有MFC的患者在下侧侧和部部门显著增加了视网膜神经纤维层 (RNFL) 厚度.
- 与对照组相比,MFC组在状细胞层 (GCL) 和内状层 (IPL) 中表现出更大的厚度,以及相比对照组显著较浅的状坑.
结论:
- 在一般人群中,MFC和CRM的流行率很低.
- MFC的存在与黄斑结构的显著变化有关,包括内视网膜加厚和减少状孔深度.
- 这些发现表明,胚胎发育过程中可能会出现发育障碍,影响质细胞迁移和亡.
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