较高的母乳面包和胺摄入量与婴儿过敏性疾病增加有关
Rachelle A Pretorius1,2, Elizabeth McKinnon1, Debra J Palmer1,2
1Telethon Kids Institute, University of Western Australia, Nedlands, Western Australia, Australia.
概括
富含胺的孕产妇饮食,在强化白面包中发现,与增加婴儿湿疹和食物过敏有关. 需要对高胺暴露的进一步研究.
科学领域:
- 围产期营养和婴儿免疫学.
- 饮食模式和免疫介导疾病.
背景情况:
- 怀孕期间母亲的饮食会影响婴儿的免疫发育.
- 由于营养物质相互作用,饮食分析是复杂的;需要采用多元组件方法.
研究的目的:
- 研究孕期晚期母亲的饮食摄入模式与婴儿免疫结果之间的关联.
- 探索特定食物组,营养素和婴儿湿疹,过敏原敏感化和食物过敏之间的联系.
主要方法:
- 一组639名孕妇通过食物频率问卷 (32-36周孕期) 提供了饮食数据.
- 计算了饮食炎症指数得分;评估了食物组,全食物和营养素的消费.
- 婴儿的结局 (湿疹,敏感化,过敏) 用共变量调整的回归模型进行分析.
主要成果:
- 较高的母亲白面包消费与增加的婴儿湿疹和IgE介导的食物过敏相关.
- 增加富含纤维的面包和豆类的摄入量与婴儿湿疹有关.
- 增加母亲的胺摄入量与父母报告的婴儿湿疹发病率较高有关.
结论:
- 在澳大利亚,较高的母乳胺摄入量,特别是来自强化面包,与婴儿湿疹和食物过敏风险的增加有关.
- 这些发现表明需要研究高胺暴露对子宫内免疫发育的影响.
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