脊髓损伤后加强:在走路时克服障碍物
Alain Frigon1, Charly G Lecomte
1Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Centre de recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.
Neural regeneration research
|September 10, 2024
概括
脊髓损伤会破坏大脑和脊髓之间的沟通,损害障碍物谈判. 本综述探讨了跨越障碍物和受伤后恢复的神经机械控制.
科学领域:
- 神经科学是一个神经科学.
- 生物力学 生物力学
- 发动机控制器的控制器
背景情况:
- 步态修改对于日常障碍物谈判至关重要.
- 脊髓损伤 (SCI) 严重影响跨越障碍物的能力.
- 跨越障碍物涉及到大脑区域的复杂的感觉运动转换,如头顶皮层,前运动皮层和运动皮层.
研究的目的:
- 为了审查跨越障碍物的神经机械控制.
- 为了解释SCI后的障碍踩踏失败.
- 讨论SCI后的障碍踩踏恢复的程度.
主要方法:
- 本综述综合了关于神经控制运动和避开障碍物的现有研究.
- 它检查了SCI对感觉运动通路的影响.
- 该审查讨论了与运动恢复和适应相关的发现.
主要成果:
- SCI破坏了大脑发送自发步态修改的运动指令的能力.
- 在SCI之后,大脑和脊髓之间的双向通信受到损害.
- 有SCI的动物和人类努力自愿调整肢体轨迹以清除障碍物.
结论:
- 了解跨越障碍物的神经机械基础对于SCI后的康复至关重要.
- 大脑 - 脊髓通信的破坏是SCI后运动缺陷的关键因素.
- 障碍物跨越能力的部分恢复可能会发生,突出潜在的治疗目标.
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