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儿科白血病患者的口腔表现:系统审查和元分析
Journal of the American Dental Association (1939)
|September 10, 2024
概括
儿童白血病患者经常经历口腔健康问题,包括治疗期间的牙和牙周炎,以及治疗后的牙异常. 早期的牙科转诊对于改善生活质量至关重要.
科学领域:
- 儿科瘤学 儿科瘤学
- 口腔医学是指口腔医学.
- 系统审查是系统的审查.
背景情况:
- 白血病是一种常见的儿科癌症,已知涉及外骨髓.
- 经常观察到口服表现,但缺乏系统的患病率数据.
- 本综述系统地评估了儿科白血病患者的口腔表现.
研究的目的:
- 为了确定诊断为白血病的儿科患者口腔表现的患病率.
- 综合现有的关于与儿科白血病相关的口腔健康并发症及其治疗的文献.
主要方法:
- 在多个数据库 (PubMed-MEDLINE,Embase等) 中进行全面的系统搜索. 和灰色的文学.
- 包括观察性研究,报告儿科白血病患者口腔病变的流行率和发生率.
- 两个独立的审稿人使用标准化的Excel电子表格提取数据.
主要成果:
- 对67项研究的分析揭示了79种不同的口腔表现.
- 在治疗期间,人们注意到脏病 (81%),牙周炎 (73%),口腔粘膜炎 (50%) 和淋巴腺病 (45%) 的高患病率.
- 在治疗后,牙异常影响了61%的患者,包括牙下形成 (40%),牙生殖 (22%),微牙 (22%).
结论:
- 儿科白血病患者在瘤治疗期间和之后表现出显著的口腔表现.
- 医疗保健专业人员应该认识到这些口腔问题,并在治疗期间促进牙科转诊.
- 牙医的参与对于支持儿科白血病患者和提高他们的生活质量至关重要.
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