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治疗模式,医疗资源利用和费用在医疗保险患者与扩散大B细胞淋巴瘤:一个回顾性索赔分析 (2015-2020) 的费用

Monika P Jun¹, Alex Mutebi¹, Anindit Chhibber¹

¹Genmab, Plainsboro, NJ, USA.

Journal of medical economics

|September 10, 2024

概括

扩散性大B细胞淋巴瘤 (DLBCL) 的经济负担在老年人中的每一条治疗线都会增加. 需要新的治疗选择,因为目前对复发性/耐药DLBCL的护理标准尚不清楚.

科学领域:

血液学血液学血液学
在瘤学瘤学.
卫生经济学卫生经济学

背景情况:

扩散性大B细胞淋巴瘤 (DLBCL) 是老年人群的重大健康问题.
了解治疗模式和经济负担对于老年人DLBCL的管理至关重要.

研究的目的:

分析美国老年人 (≥66岁) 的治疗模式,医疗资源利用率 (HCRU) 和DLBCL的经济负担.
在这个人口群体中描述与DLBCL不同疗法相关的成本.

主要方法:

对医疗保险服务费索赔数据 (2015-2020年) 的回顾性分析.
包括连续招募前和后DLBCL诊断的患者.
计算每患者每月 (PPPM) HCRU 和 2022 美元的成本.

主要成果:

11,893名患者接受了≥1线治疗;R-CHOP在1L中很常见,2L/3L中的bendamustine±rituximab.
住院病例随着治疗线路的增加 (1L中的39.6%到3L中的47.8%).
平均PPPM成本在每条线上显著上升,在3L中达到47,064美元,3L中的CAR T治疗成本为153,847美元PPPM.

结论:

在老年患者中,DLBCL的经济负担随着随后的治疗线路而升级.
在复发性/耐药性DLBCL的第三线治疗中缺乏明确的护理标准,凸显了对新型治疗选择的需求.

关键词:

我已经开始了,我已经开始了.第111章这是一件好事一千一百一十,就是一百一十.在1919年,我开始了我的生活.大型B细胞淋巴瘤嵌合式抗原受体疗法嵌合式抗原受体疗法疾病的成本.经济负担经济负担无事件生存率无事件生存率医疗保健资源利用率医疗保健资源利用率住院治疗住院治疗非霍奇金淋巴瘤的非霍奇金淋巴瘤.护理的标准护理的标准治疗模式治疗模式

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