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肝脏细分体积及其与5年预后关系

Damiano Catucci^1,2, Joris Hrycyk³, Naomi Franziska Lange⁴

¹Department of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 10, 3010, Bern, Switzerland. damiano.catucci@insel.ch.

Abdominal radiology (New York)

|September 10, 2024

概括

尾皮与右叶比率 (CRL-R) 和肝部细分体积比率 (LSVR) 在CT扫描上有效预测慢性肝病 (CLD). 这些比率也与患者的生存结果相关,有助于对CLD患者的预后.

科学领域:

放射学放射学是一门学科.
肝病学肝病学是一种肝病学.
医疗成像医学成像

背景情况:

慢性肝病 (CLD) 的诊断和预后至关重要.
常规腹部CT扫描提供了非侵入性评估的潜力.
目前正在积极寻找CLD的预测性成像生物标志物.

研究的目的:

为了评估尾状细胞与右叶比率 (CRL-R) 和肝脏细分体积比率 (LSVR) 对CLD的预测值.
评估CRL-R和LSVR与CLD患者5年无补偿和无移植生存时间的相关性.

主要方法:

对108名健康对照和98名CLD患者的回顾性分析.
腹部CT扫描分析用于CRL-R和LSVR测量.
克鲁斯卡尔-瓦利斯和ROC分析确定了切断值;卡普兰-梅尔评估了生存率.

主要成果:

无论是CRL-R还是LSVR,在CLD严重程度组之间都显示出显著的差异 (p < 0.001).
CRL-R>0.99 (AUC=0.75) 和LSVR>0.37 (AUC=0.80) 预测了晚期的CLD.
结合高CRL-R和LSVR与显著较低的5年生存率相关 (31%无补偿,41%无移植).

结论:

CRL-R和LSVR是用于预测常规CT扫描中的CLD的有价值的成像生物标志物.
这些比率表明了CLD的显著预测能力.
联合CRL-R和LSVR与CLD患者的长期生存结果有关.

关键词:

计算机断层扫描 (CT) 是一种计算机断层扫描.肝脏疾病是一种肝脏疾病.这是一种非侵入性的方法.门口高血压的高血压.预后预后预测预测

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