在临床实验室安全有效地验证,实施和监控机器学习解决方案
Nicholas C Spies1, Christopher W Farnsworth2, Sarah Wheeler3
1Department of Pathology, University of Utah School of Medicine/ARUP Laboratories, Salt Lake City, UT, United States.
Clinical chemistry
|September 10, 2024
概括
在临床实验室中实施机器学习需要仔细验证,整合和持续监测. 本综述指导病理学家通过这些关键步骤,在实验室医学中负责任地采用人工智能.
科学领域:
- 病理学和实验室医学的医学.
- 医疗保健中的人工智能
- 临床信息学 临床信息学
背景情况:
- 机器学习 (ML) 对改善病理学和实验室操作具有重大潜力.
- 尽管有大量的概念验证研究,但实验室中ML的临床实施仍然有限,原因是验证,实施和监测挑战.
- 弥合ML理论和实际临床应用之间的差距对于负责任的采用至关重要.
研究的目的:
- 概述临床实验室中验证机器学习解决方案的关键考虑因素.
- 详细介绍了在实体实验室环境中实施验证的ML工具的实际方面.
- 强调 ML 应用在实施后的持续监测和更新的重要性.
主要方法:
- 综合验证框架包括研究设计,数据工程,度量选择,概括性,公平性和可解释性.
- 讨论成功部署ML的跨学科角色和责任.
- 强调常规的性能监测和必要的更新,以保持持续的疗效.
主要成果:
- 为ML验证提供了一个结构化的方法,涵盖数据和算法的批判性评估.
- 确定在生产环境中有效实施ML的基本角色和术语.
- 强调需要对ML解决方案进行持续的性能监测和维护.
结论:
- 本综述为临床实验室中机器学习的有效和负责任的验证,实施和监测提供了实际指导.
- 它旨在消除该过程的神秘性,使ML能够更广泛地被采用,以改善实验室诊断和操作.
- 重点是弥合理论ML概念和现实世界临床实验室实践之间的差距.
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