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Updated: Jun 13, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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与林奇综合征相关的基因组变异

Robert Botea1, Madalina Piron-Dumitrascu1, Tiberiu Augustin Georgescu2

  • 1Dept. of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest; Dept. of Obstetrics and Gynecology, Alessandrescu-Rusescu National Institute of Mother and Child Health, Bucharest, Romania.

Journal of gastrointestinal and liver diseases : JGLD
|September 10, 2024
PubMed
概括

与林奇综合征相关的子宫内膜癌与结直肠癌具有共同的基因组变异,特别是在不匹配修复基因中. 在PIK3CA,PTEN,FBN1和SPARC中的新突变表明这些遗传性癌症的新治疗点.

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