在受监督注射设施中通过可穿戴胸部传感器在高风险阿片类药物使用者中检测过量:观察性研究协议
Basak Tas1, Will Lawn2, Marianne Jauncey3
1National Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
JMIR research protocols
|September 10, 2024
概括
一种新的可穿戴生物传感器PneumoWave正在开发中,通过实时测量胸部运动来检测阿片类药物过量. 这项技术旨在改善早期干预并减少因阿片类药物诱导的呼吸系统抑郁 (OIRD) 造成的死亡人数.
科学领域:
- 可穿戴生物传感器技术
- 发现阿片类药物过量剂量的检测
- 呼吸系统抑郁的监测监测呼吸系统的抑郁.
背景情况:
- 过量服用阿片类药物是一个关键的全球健康问题,在美国每年造成10万多人死亡.
- 现有的过量检测方法缺乏实时能力,延迟了关键干预.
- PneumoWave胸部生物传感器是一款用于持续监测的新型可穿戴设备.
研究的目的:
- 开发和完善一种用于检测阿片类药物诱导的呼吸抑制 (OIRD) 的算法.
- 使用胸部运动数据将OIRD与非致命的阿片类药物使用模式区分开来.
- 为了评估参与者对PneumoWave胸部生物传感器的接受度.
主要方法:
- 6个月的观察性研究,涉及安全注射设施 (SIF) 的参与者.
- 参与者在阿片类药物注射事件期间佩戴PneumoWave生物传感器,以捕获胸部运动数据.
- 生物传感器数据与工作人员识别的过量事件进行比较;可接受性通过问卷进行评估.
主要成果:
- 截至2024年4月,已有47名参与者注册,收集了来自1145个注射事件的数据.
- 在参与者中记录了10次过量服用事件 (17名女性,30名男性,平均年龄45岁).
- 数据分析正在进行中,以完善过量检测算法.
结论:
- 该协议支持可穿戴技术的进步,以预防SIF的阿片类药物过量服用.
- 胸壁运动数据将训练一个算法,通过生物传感器实时检测过量.
- 这项研究为OIRD和生物传感器在及时干预方面的潜力提供了重要的见解.
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