梨多氧化脂肪醇的生物可访问性
Nawaz Ahmed1, Richard W Smith2, Peter X Chen1
1Department of Food Science, University of Guelph, Guelph, Ontario, N1G 2W1, Canada.
Food chemistry
|September 10, 2024
概括
像梨和梨这样的梨多氧化脂肪酒精 (PFAs) 是从梨肉质中生物可获得的. 这项研究表明,它们可以有效地被吸收,支持它们在营养和健康中的作用.
科学领域:
- 营养生物化学 营养生物化学
- 线粒体的新陈代谢
- 饮食中的生物可用性
背景情况:
- 梨衍生的多氧化脂肪酒精 (PFAs),包括梨烯和梨丁,因其调节线粒体代谢的潜力而得到认可.
- 这些化合物已证明可以诱导选择性白血病细胞死亡并逆转饮食诱导的肥胖病理.
- 从梨纸中获得这些特定PFA的生物可访问性以前没有报告过.
研究的目的:
- 为了研究梨纸中梨烯和梨丁的生物可访问性.
- 为了比较梨纸中的这些PFA的生物可访问性与配制的微乳液.
- 评估梨作为这些生物活性化合物的饮食来源的潜力.
主要方法:
- 使用了体外消化模型,包括TNO动态肠道模型-1 (TIM-1) 和静态消化.
- 溶解的哈斯梨粉末经过消化,以评估PFA释放.
- 在油与水微乳液中配制的纯梨和梨 (梨B) 也使用TIM-1进行了消化.
主要成果:
- 脂质性胃肠道酶促进了梨粉中的梨烯 (55%) 和梨丁 (50%) 的可感知的生物可访问性.
- 与梨果粉相比,阿沃卡丁B的微乳液配方具有大约15%的更高生物可访问性.
- 梨纸和微乳液配方都显示出梨PFAs的饮食来源的潜力.
结论:
- 梨衍生PFAs,梨和梨,是通过体外消化通过梨纸生物可获得的.
- 在微乳液中配制这些PFA可以提高它们的生物可访问性.
- 这项研究强调了饮食中长链脂肪酒精的营养意义,需要进一步研究.
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