通过室温盐水输出的肺心输出是准确的,并跟踪麻醉狗的方向变化
Cheyenne J Cannarozzo1, Joaquin Araos2, Manuel Martin-Flores2
1Cornell University Hospital for Animals, College of Veterinary Medicine, Cornell University, Ithaca, NY.
American journal of veterinary research
|September 10, 2024
概括
用室温盐水进行肺间热稀释,可以准确测量心脏输出量 (CO),并跟踪变化. 持续的CO监测显示出高百分比的误差,这表明本研究的可靠性较低.
科学领域:
- 心血管生理学心血管生理学
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
背景情况:
- 心脏输出 (CO) 监测对于指导血液动力学管理至关重要.
- 使用冷盐水 (COICED) 进行肺间热稀释 (TPTD) 是测量CO的标准方法.
- 正在探索其他方法,如室温盐水 (CORT) 和连续CO (CCO),以提高临床适用性.
研究的目的:
- 在麻醉狗中评估TPTD与CORT和波形衍生的CCO与COICED的性能.
- 为了确定与已建立的COICED方法相比,CORT和CCO的准确性和跟踪能力.
主要方法:
- 八只麻醉的比格尔犬被仪器用于血液动力学监测.
- 用TPTD与冷盐水 (COICED),室温盐水 (CORT) 和来自脉冲波形的连续CO (CCO) 来测量心脏输出.
- 测量是在基线和各种血液动力学挑战期间进行的,包括血管活性药物输注和出血.
主要成果:
- 使用CORT的TPTD显示了微不足道的偏差和与COICED的良好一致 (百分比误差:17.7%).
- 在CORT和COICED之间的一致率高达95%.
- 与COICED相比,连续CO (CCO) 显示出很大的百分比误差 (66.6%) 和较低的跟踪能力 (68%一致性).
结论:
- 用室温盐水进行肺间热稀释是一种准确可靠的方法来监测心脏输出.
- CORT消除了对冰制剂的需求,提供了一个更方便的临床选择.
- 使用脉冲波分析进行持续的CO监测显示,这种犬类模型的准确性和跟踪能力存在重大限制.
关键词:
亚塞普罗玛 (acepromazine) 是一种药物.心脏输出的心脏输出.血液动力学 血液动力学诺尔阿皮内弗林 (norepinephrine) 是一种可怕的药物.烯 (phenylephrine) 是一种可靠的药物.更多相关视频
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相关概念视频
01:11Cardiac Output and Stroke Volume
Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical cardiac output averages...
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01:19Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...