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分裂增强分子成像 (SEMI) 技术

Jeremy M Quintana1,2, Jonathan C T Carlson1,3, Ella Scott1

  • 1Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, CPZN 5206, Boston, Massachusetts 02114, United States.

Bioconjugate chemistry
|September 10, 2024
PubMed
概括

一种新的裂变增强分子成像 (SEMI) 方法可以在PET成像或放射治疗治疗后快速消除放射性核素. 这种技术利用生物对角连接剂来降低患者的毒性,并提高核医学应用中的安全性.

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The ionization of a molecule into a molecular ion inside the mass spectrometer causes instability in the molecule's structure due to the loss of an electron. This eventually leads to the fragmentation or breaking of some bonds in the molecule. The fragmentation occurs predominantly at specific bonds to yield relatively stable fragments.
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