需要,偏好和患者参与一项随机对照试验后neoadjuvant完整的瘤反应:食道癌患者的定性研究
Manuel Czornik1, Joachim Weis2, Andrea Kiemen3
1Department of Psychiatry and Psychotherapy/Division for Interventional Biological Psychiatry, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
概括
患有食道癌症 (EC) 的患者对手术与主动监测存在担忧. 以患者为中心的信息对于治疗决策和临床试验参与至关重要.
科学领域:
- 在瘤学瘤学.
- 以患者为中心的护理
- 临床试验设计 临床试验设计
背景情况:
- 非转移性食道癌 (EC) 患者面临治疗选择后的新辅助疗法:标准手术或积极监测.
- 这两种选择在总生存率上都被认为是相当的,需要以患者为中心的决策.
研究的目的:
- 为食道癌治疗替代方案开发以患者为中心的信息.
- 探索患者对主动监测和手术的态度,以及参与随机对照试验 (RCT) 的态度.
主要方法:
- 定性前性横截面研究.
- 采访了11名食道癌患者,询问了他们对治疗的偏好和参与RCT的情况.
- 分析患者的担忧和动机.
主要成果:
- 手术的关键问题包括术后损伤和生活质量.
- 在积极监测下,对复发和进展的担忧很突出.
- 参与RCT的动机包括为科学做出贡献和寻求优质疗法;障碍包括缺乏主动治疗选择.
结论:
- 医疗沟通必须适应患者的专业知识和情绪状态.
- 改进以患者为中心的信息可以提高癌症临床试验的招聘.
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