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Updated: Jun 13, 2025

CD Spectroscopy to Study DNA-Protein Interactions
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在poly (ADP-ribose) 中,阴离子诱导的分子内线圈转换为球体

Tong Wang1, Kush Coshic2, Mohsen Badiee3

  • 1School of Applied and Engineering Physics, Cornell University, Ithaca, NY, 14853, USA.

Nature communications
|September 10, 2024
PubMed
概括

聚ADP- рибо (PAR) 结构因长度而异,影响蛋白质结合. 这项研究揭示了PAR链的长度依赖的紧缩和捆绑,这对于理解其在DNA/RNA代谢和疾病中的生物学作用至关重要.

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