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Updated: Jun 13, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

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通过绑定站点描述器全面检测和表征人类可用药物的口袋

Arnau Comajuncosa-Creus1, Guillem Jorba1, Xavier Barril2,3

  • 1Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain.

Nature communications
|September 10, 2024
PubMed
概括

PocketVec使用反向虚拟选来识别可用药物的蛋白质口袋. 这种方法揭示了结合点之间的新奇相似之处,有助于药物发现和化学探针开发.

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