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Updated: Jun 13, 2025

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调节了BCOR-PRC1.1酶核与KDM2B的结合,通过液-液相分离

Rui Chen1,2, Feng Shen1,2, Yulong Zhang2

  • 1Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.

Communications biology
|September 10, 2024
PubMed
概括

离子调节了BCOR-PRC1.1复合物的招募到KDM2B的目标. 在BCOR上负电荷的区域是这种相互作用的关键,影响发育和癌症中的转录控制.

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