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Updated: Jun 13, 2025

Differentiation of Functional Osteoclasts from Human Peripheral Blood CD14+ Monocytes
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托法西提尼布对患有类风湿性关节炎的患者骨循环标记物和骨调节剂的影响

Giovanni Adami1, Giovanni Orsolini2, Maurizio Rossini2

  • 1Rheumatology Unit, University of Verona, Pz Scuro 10, Verona, 37134, +0458124049, Italy. giovanni.adami@univr.it.

BMC rheumatology
|September 10, 2024
PubMed
概括

在类风湿性关节炎 (RA) 中,托法西替尼治疗增加了硬质素,但减少了骨形成标志物. 重要的是,这种JAK抑制剂不会导致显著的骨损失,这表明RA患者对骨代谢有复杂的影响.

关键词:
骨矿物质密度 (BMD) 是指骨矿物质的密度.骨代谢 炎症 骨代谢 炎症骨循环标记器 (BTMs) 是一种骨循环标记器.托法西提尼布 (tofacitinib) 是一种可靠的药物.

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