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一个来自患者的细胞模型用于IDH突变质瘤的恶性转变

Olga Kim1, Zach Sergi1, Guangyang Yu1

  • 1Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 1142A, 37 Convent Drive, Bethesda, MD, 20892, USA.

Acta neuropathologica communications
|September 10, 2024
PubMed
概括

研究人员从单个患者中开发了匹配的3D细胞模型.

关键词:
3D细胞模型 3D细胞模型高度质瘤 (HGG) 是一种高度质瘤.超变异体表型 (HMP) 是一种超变异体表型.有IDH突变的质瘤.低度质瘤 (LGG) 是一种轻度质瘤.恶性转化 (MT) 是一种恶性转化.匹配的来自患者的细胞匹配.瘤突变负担 (TMB) 是指瘤突变负担.

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