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相关概念视频

Inhibitors of Viral Protein Synthesis01:30

Inhibitors of Viral Protein Synthesis

58
Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
58

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Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
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一例因梅尔法兰引起的干扰素玛释放试验结果异常下降的病例.

Gangfeng Li, Tao Lu, Ningping Shan

    Clinical laboratory
    |September 11, 2024
    PubMed
    概括

    对多发性骨髓瘤的梅尔法兰治疗可能会导致骨髓抑制,导致干扰素玛释放试验 (IGRA) 的错误负结果. 这凸显了在接受这种化疗的患者中需要仔细解释IGRA测试的必要性.

    科学领域:

    • 免疫学 免疫学 免疫学
    • 在瘤学瘤学.
    • 临床诊断 临床诊断 临床诊断

    背景情况:

    • 干扰素释测定 (IGRA) 对于诊断结核病和潜在感染至关重要.
    • 准确的IGRA结果对于有效的患者管理至关重要.

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