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Updated: Jun 13, 2025

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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Cpd861 向BCL2缓解肝纤维化:网络药理学,孟德尔随机化和分子对接机制

Yaning Lyu1,2, Xifeng Liang1,2, Shuang Gao3

  • 1School of Nursing, Shandong Second Medical University, Weifang, 261021, Shandong, China.

Current pharmaceutical design
|September 11, 2024
PubMed
概括

化合物861 (Cpd861) 是一种传统的中国草药,显示出治疗肝纤维化 (HF) 的潜力. 网络药理学和门德尔随机化确定了MDM2和BCL2作为关键标,Cpd861化合物与BCL2结合.

关键词:
肝脏纤维化 肝脏纤维化化合物 861 颗粒颗粒门德尔的随机化是门德尔的随机化分子对接的分子对接.网络药理学 网络药理学传统的中国草药化合物.传统的中国草药化合物.

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