Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Overview of Cell Death01:30

Overview of Cell Death

Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the 20th century...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

An interpretable machine learning model for predicting myocardial injury in patients with high cervical spinal cord injury.

Frontiers in genetics·2025
Same author

"Smart" Nerves Sprout and Assemble in an Extracellular Matrix-Based 3D Nerve-in-a-Chip Microfluidic Model.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Dynamic changes in liver stiffness measurement by 2D shear-wave elastography predict hepatocellular carcinoma in patients with chronic hepatitis B and well-controlled viremia: a retrospective study.

BMC gastroenterology·2025
Same author

Predicting hourly indoor ozone concentrations with sensor-based measurements and easily accessible predictors.

Eco-Environment & Health·2025
Same author

The Association Between Health Literacy and Depressive Symptoms With the Mediation Role of Family Health and Perceived Social Support in Older Adults: A Nationwide Cross-Sectional Study in China.

International journal of geriatric psychiatry·2025
Same author

An investigation of the relationship and pathways of influence between body mass index, motor coordination, and health-related physical fitness index in preschool children.

Frontiers in public health·2025

相关实验视频

Updated: May 8, 2026

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

9.5K

RCDdb:一个手动策划的数据库和分析平台,用于调节细胞死亡.

Xiaopeng Wang1,2,3, Qing Wang4, Jun Zhao5

  • 1State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.

Computational and structural biotechnology journal
|September 11, 2024
PubMed
概括

一个新的数据库,RCDdb,目录调节细胞死亡 (RCD) 标记基因,并提供分析工具. 该资源有助于研究人员了解疾病治疗的细胞死亡机制.

关键词:
分析平台是一个分析平台.生物信息学是一种生物信息学.数据库数据库数据库是一个数据库.调节的细胞死亡.

更多相关视频

Measuring Composition of CD95 Death-Inducing Signaling Complex and Processing of Procaspase-8 in this Complex
07:17

Measuring Composition of CD95 Death-Inducing Signaling Complex and Processing of Procaspase-8 in this Complex

Published on: August 2, 2021

2.5K
MEDUSA for Identifying Death Regulatory Genes in Chemo-genetic Profiling Data
07:17

MEDUSA for Identifying Death Regulatory Genes in Chemo-genetic Profiling Data

Published on: February 7, 2025

405

相关实验视频

Last Updated: May 8, 2026

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

9.5K
Measuring Composition of CD95 Death-Inducing Signaling Complex and Processing of Procaspase-8 in this Complex
07:17

Measuring Composition of CD95 Death-Inducing Signaling Complex and Processing of Procaspase-8 in this Complex

Published on: August 2, 2021

2.5K
MEDUSA for Identifying Death Regulatory Genes in Chemo-genetic Profiling Data
07:17

MEDUSA for Identifying Death Regulatory Genes in Chemo-genetic Profiling Data

Published on: February 7, 2025

405

科学领域:

  • 生物医学研究的研究.
  • 分子生物学分子生物学
  • 基因组学就是基因组学.

背景情况:

  • 调节细胞死亡 (RCD) 对于多细胞生物的发育和恒温至关重要.
  • 了解RCD机制对于治疗癌症和神经退行性疾病等疾病至关重要.
  • 目前的数据存储库缺乏全面的RCD数据和分析工具.

研究的目的:

  • 建立调节细胞死亡数据库 (RCDdb),这是所有RCD类型的第一个手动注释数据库.
  • 为RCD研究提供全面的注释和分析功能.

主要方法:

  • 从2180篇文章中编制了15个RCD类型的3090个标记基因注释.
  • 关于疾病,药物,途径,蛋白质和基因表达的综合数据.
  • 开发了49种可视化方法和3种在线分析工具.

主要成果:

  • 该RCDdb包含RCD标记基因的大量手动策划的注释.
  • 它提供各种可视化选项和强大的在线分析工具.
  • 该数据库提供了一个用户友好的界面,用于数据探索和分析.

结论:

  • RCDdb显著提高了研究人员研究细胞死亡机制的能力.
  • 该资源加速了开发RCD相关疾病治疗策略的进展.
  • RCDdb是RCD研究和药物发现的宝贵平台.