液回收自移植用于治疗骨肉瘤是否会影响局部复发率? 一个系统的审查
Ana Cecilia Belzarena1, James L Cook1
1Department of Orthopaedic Surgery, University of Missouri Hospital, Columbia, MO, United States.
Journal of bone oncology
|September 11, 2024
概括
液回收自体移植为原发性骨肉瘤提供了一个有前途的四肢救援重建选择. 与人工植入物相比,这种技术显示出有利的局部复发率,因此需要进一步考虑.
科学领域:
- 整形瘤学 整形瘤学
- 手术重建手术重建的方法
- 生物材料科学 生物材料科学
背景情况:
- 手术切除是治疗原发性骨肉瘤的黄金标准.
- 肢体救援重建方法缺乏共识标准.
- 液循环自移植技术于2005年引入.
研究的目的:
- 系统地审查使用液回收自体移植用于原发性骨肉瘤的四肢救援重建的局部复发率.
- 为了将这些比率与其他重建方法进行比较.
主要方法:
- 在PubMed和谷歌学者 (2008-2023) 的系统文献搜索.
- 包括用液回收自体移植治疗的四肢/骨盆初级骨肉瘤的研究.
- 分析了包括286名患者在内的16项研究.
主要成果:
- 在4年内,在8.7%的患者 (25/286) 观察到局部复发.
- 这一比率与人工植入物中15-30%的复发率相比较有利.
- 液回收自体移植显示了类似或较低的局部复发率.
结论:
- 液循环自移植技术为骨肉瘤治疗提供了一个可行的肢体救援选择.
- 它在成本,可用性和生物/外科益处方面具有优势.
- 对于已显示的患者,需要进一步考虑.
相关概念视频
Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...


