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子宫内膜模式预测了单胞胎冷胚胎转移中的妊娠结果:对1383个周期的分析

Kazutaka Kuramoto^1,2, Norio Hamada¹, Keiko Kawamura¹

¹Department of Obstetrics and Gynecology, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.

Reproductive medicine and biology

|September 11, 2024

概括

叶子图案 (Lf) 的子宫内膜与单胞胎冷胚胎移植 (sbFET) 中更高的怀孕和活产率有关. 没有叶子的图案表明成功率较低,流产风险更高.

科学领域:

生殖医学生殖医学
胚胎学胚胎学
产科和妇科产科和妇科

背景情况:

子宫内膜模式对于胚胎植入成功至关重要.
之前的研究没有根据转移的胚芽细胞的数量来区分结果.
了解单胞胎冷胚胎转移 (sbFET) 中子宫内膜接受度是必不可少的.

研究的目的:

在sbFET中调查子宫内膜模式与怀孕结果之间的关联.
澄清特定子宫内膜成像特征在预测成功中的作用.
提供与冷胚胎移植中的子宫内膜形态相关的怀孕率数据.

主要方法:

对1383个单胞胎胚胎冷胚胎转移周期的分析,对35岁以下的患者进行分析.
根据中央回声线对子宫内膜图案进行分类,分为叶 (Lf),部分Lf和非Lf.
子宫内膜模式与临床怀孕,活产和流产率的相关性.

主要成果:

叶子模式 (Lf) 显示了最高的临床怀孕率 (70.4%) 和活产率 (56.3%).
子宫内膜中央回声线 (Lf>部分Lf>非Lf) 的分辨率下降与明显较低的成功率有关.
非Lf模式的临床怀孕率 (28.3%) 和活产率 (15.0%) 最低,流产率高 (47.1%).

结论:

非叶子 (非Lf) 子宫内膜模式与显著减少的怀孕和活产率有关.
非Lf的子宫内膜表达可能表明胚胎植入的最佳条件不足.
这项研究提供了基于子宫内膜模式的sbFET怀孕结果的宝贵见解.

关键词:

艺术艺术艺术艺术胚胎囊细胞转移是什么意思怀孕的结果.单个胚胎转移是一个胚胎转移.超声波超声波是指超声波的使用.

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