在连续的泰达爆发刺激后,尾皮层的兴奋性变化
Khayala Aghamirzayeva1, Çağrı Mesut Temuçin1,2, Fatma Gökçem Yıldız1,2
1Hacettepe University, School of Medicine, Department of Neurology, Ankara, Turkey.
Noro psikiyatri arsivi
|September 11, 2024
概括
在健康个体中,皮皮层的持续爆刺激 (cTBS) 增加了基值. 这种神经刺激技术有效调节视觉皮层刺激性,正如基值变化所示.
科学领域:
- 神经科学是一个神经科学.
- 视觉皮层研究 视觉皮层研究
- 大脑刺激 大脑刺激
背景情况:
- 对视觉皮层的重复性横磁性刺激 (rTMS) 影响的研究不足.
- 连续爆刺激 (cTBS) 是一种特定的rTMS协议.
研究的目的:
- 通过使用cTBS来调查尾皮层的神经生理学变化.
- 评估cTBS对健康受试者的视觉皮层刺激性的影响.
主要方法:
- 25名健康参与者接受了真实和假的cTBS在皮层上.
- 在刺激之前和之后测量了素值和视觉唤起潜力 (VEP).
- 分析了VEP习惯性,P100延迟时间和N75-P100振幅.
主要成果:
- 在真实cTBS之后,素值显著增加.
- 在真实和虚假条件下均发生了VEP习惯,没有显著差异.
- 在条件之间没有发现P100延迟或N75-P100振幅的显著差异.
结论:
- 素值测量证实了由cTBS进行的脑后皮层兴奋度调节.
- 在健康个体中,cTBS显示出改变视觉皮层功能的潜力.
更多相关视频
08:23A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
11.1K
10:25Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
Published on: June 5, 2017
13.9K
相关概念视频
Thermosensation
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
Motor Unit Stimulation
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Muscle Stimulation Frequency
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Sympathetic Activation
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
Inflammatory Response
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...
