在治疗牛皮后肺结核的重新激活:是时候考虑进行常规的肺结核查了吗?
Lucinda Adams1, Emma L Smith2, Dev Tilakaratne1
1Department of Dermatology, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
The Australasian journal of dermatology
|September 11, 2024
概括
治疗牛皮的阿普雷米拉斯特可能会增加结核病的风险. 在开始服用这种药物之前,建议对潜伏结核病感染进行查,尽管之前有试验数据.
科学领域:
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
背景情况:
- 阿普雷米拉斯特是一种口服牛皮治疗药物,可以抑制TNF-α等促炎因素.
- 在控制Mycobacterium结核病感染方面,TNF-α起着至关重要的作用.
- 目前的指导方针不建议在启动apremilast之前对潜伏结核病感染 (LTBI) 进行查,基于先前的随机对照试验 (RCT).
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