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Updated: Jun 13, 2025

Using the E1A Minigene Tool to Study mRNA Splicing Changes
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MBNL拼接因子调节了骨肌肉的微转录组

Agnieszka Piasecka1, Michał W Szcześniak2, Michał Sekrecki1

  • 1Laboratory of Gene Therapy, Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614 Poznań, Poland.

Nucleic acids research
|September 11, 2024
PubMed
概括

肌盲类拼接调节器 (MBNLs) 控制RNA处理. 在1型肌肉性缩症 (DM1) 中,MBNL 隔离破坏了骨肌肉中的微RNA (miRNA) 调节,影响了疾病的进展.

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