肺动脉高血压中的心电图预后标记:RS时间
Emin Koyun1, Anil Sahin2, Ahmet Yilmaz2
1Sivas Numune Hospital, Department of Cardiology, Sivas - Turquia.
Arquivos brasileiros de cardiologia
|September 11, 2024
概括
在心电图上,QRS开始和S波峰值 (RS时间) 之间的较长时间表明肺动脉高血压患者的预后不佳. 这种简单的,非侵入性的措施有助于评估疾病的进展.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 肺高血压涉及右心室重塑,影响疾病预后.
- 电心图参数可以反映复杂的心脏变化,如重塑期间的过度缩小和扩张.
研究的目的:
- 研究肺动脉高血压 (PAH) 患者的预后和心电学参数之间的关系.
- 确定用于预测PAH结果的非侵入性标记物.
主要方法:
- 在2010年至2022年期间诊断的PAH患者的回顾性研究.
- 在生存组之间对心电图,人口图,心声图,导管和血液参数进行比较.
- 进行了多变量Cox回归和生存分析.
主要成果:
- RS时间,6分钟步行测试,肺动脉平均压力和心周溢血独立与生存相关 (p<0.05).
- RS时间显示了最高的诊断性能 (AUC:0.832).
- 较长的RS时间 (切断点59.5毫秒) 与较差的存活率显著相关 (HR:0.06 [0.02-0.17],p < 0.001).
结论:
- 较长的RS时间是肺动脉高血压预后不佳的重要预测因素.
- 电心电图提供了一种简单的,非侵入性的方法来评估PAH疾病的过程和患者的结果.
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