戒烟与代谢综合征风险:一个元分析
1Department of Family Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.
Medicine
|September 11, 2024
概括
戒烟在短期内增加了代谢综合征 (MS) 的风险,特别是在男性中. 然而,随着戒烟时间的延长,这种风险显著减少,这凸显了持续戒烟努力的重要性.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 戒烟的研究 戒烟的研究
背景情况:
- 吸烟是代谢和心血管疾病的主要危险因素.
- 戒烟可以降低这些风险,但通常会因相关的体重增加而受到阻碍.
- 减肥后的体重增加可能会增加代谢综合征 (MS) 的风险,此前的研究结果不一致.
研究的目的:
- 进行一项元分析,评估戒烟与代谢综合征 (MS) 之间的关联.
- 澄清戒烟与患MS的风险之间的关系.
主要方法:
- 在Medline,Embase,Cochrane图书馆和CINAHL数据库中进行全面的文献搜索,直到2023年4月.
- 包括将戒烟和MS风险与活跃吸烟进行比较的研究.
- 使用纽卡斯尔-太华尺度和通过随机效应模型进行元分析的方法质量评估.
主要成果:
- 对14项研究的总体分析显示,与活跃吸烟者相比,前吸烟者患MS的风险增加 (综合RR:1.18,95%CI:1.08-1.29).
- 对13项男性研究的小组分析发现,前吸烟者和吸烟者之间MS风险没有显著差异 (合并RR:1.05,95%CI:0.95-1.17).
- 在男性中,MS风险随着停产期≤15年而增加 (合并RR:1.26,95%CI:1.01-1.56) 但随着停产>15年而减少 (RR:0.84,95%CI:0.70-1.00).
结论:
- 与活跃吸烟相比,在戒烟的初始阶段观察到代谢综合征 (MS) 的风险增加.
- 与戒烟相关的MS风险随着戒烟持续时间的增加而变得不那么重要.
- 持续戒烟至关重要,因为长期的好处超过了代谢综合征的初始风险.
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