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在儿科神经炎症疾病中使用B细胞枯竭疗法

Helen C Wu1, Grace Y Gombolay2, Jennifer H Yang3

  • 1Department of Neurology, Oregon Health & Science University, Portland, OR, USA. wuhel@ohsu.edu.

Current neurology and neuroscience reports
|September 11, 2024
PubMed
概括

像抗CD20和抗CD19这样的B细胞枯竭疗法对于儿科自身免疫疾病是有效的. 仔细管理副作用,如输液反应和感染,确保儿童的安全性和耐受性.

关键词:
B细胞枯竭疗法是一种B细胞枯竭疗法.伊内比利祖马布 (inebilizumab) 是一种药物输液疗法是一种输液疗法.这就是Ocrelizumab.这就是Ofatumumabumab.儿科脱髓化疾病 儿科脱髓化疾病儿科神经炎症疾病 儿科神经炎症疾病里图西马布 (Rituximab) 是一种药物.在Ublituximab中使用.抗CD 19治疗的治疗方法.抗CD20治疗的治疗方法

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...