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认知储备对解释iNPH患者双重任务行走表现的贡献:与其他认知,功能和社会人口统计学变量进行比较
Elodie Piche1,2, Stephane Armand3, Gilles Allali4
1Université Côte d'Azur, LAMHESS, Nice, France. piche.e@chu-nice.fr.
Aging clinical and experimental research
|September 11, 2024
概括
认知储备 (CR) 在异常性正常压力脑症 (iNPH) 患者中显著影响双重任务行走,但在健康对照中并非如此. 通过生活方式干预来增强CR可能有助于减轻与年龄相关的iNPH功能衰退.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 康复科学 康复科学 康复科学
背景情况:
- 异常正常压力脑症 (iNPH) 是一种常见的神经疾病,具有诊断挑战.
- 双任务 (DT) 步行是iNPH的公认指标,但认知储备 (CR) 对DT表现的影响尚未完全理解.
研究的目的:
- 研究认知储备 (CR) 在预测双任务 (DT) 步行表现中的作用.
- 在健康对照组 (HC) 和iNPH患者 (iNPH-P) 之间比较CR对DT行走的贡献.
主要方法:
- 评估了68名iNPH患者和28名HC在单任务和四个DT行走条件下.
- 在涉及计数,倒计数,动物命名和字母命名的任务中评估行走速度.
- 在HC和iNPH-P之间,以及在iNPH-P内与其他变量之间的CR对步行速度的影响进行了比较.
主要成果:
- 认知储备 (CR) 在iNPH患者的单个和DT步行速度上显示出中度,显著的影响 (p < .001).
- 在健康对照组中,CR和步行速度之间没有发现显著的关系.
- CR是解释iNPH患者走路速度的一个主要因素,特别是在考虑NPH尺度时.
结论:
- 认知储备在iNPH患者的功能表现中起着至关重要的作用.
- 旨在增强CR的干预措施,如体育活动计划,可以帮助防止与年龄相关的功能衰退.
- 这些发现支持开发计划,丰富iNPH患者的社会,身体和认知资源.
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