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Updated: Jun 13, 2025

Gene Transfer for Ischemic Heart Failure in a Preclinical Model
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卡洛因通过调节SIRT1/FOXD3/SERCA2a通路来减轻心肌梗塞后缺血性心力衰竭

Zijing Chen1, Haojie Yao1, Xiaowei Yao1

  • 1State Key Laboratory of Traditional Chinese Medicine Syndrome, Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China, Guangdong Key Laboratory for translational Cancer research of Chinese Medicine, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|September 11, 2024
PubMed
概括

卡洛 (CAL) 通过上调SIRT1/FOXD3/SERCA2a通路来改善缺血性心力衰竭中的心脏功能. 这种天然化合物增强了射出分数,减少了心脏纤维化,提供了潜在的新疗法.

关键词:
卡洛托普林是一种卡洛托普林.这就是FOXD3D3的意思.缺血性心力衰竭是因为缺血性心力衰竭.这就是 SERCA2a.一个SIRT1系统.

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