暴露于急性环境温度极端和新生儿重症监护室入院:一个案例交叉研究
Sarah LaPointe1, Jing Nie1, Danielle R Stevens2
1Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY, USA.
The Science of the total environment
|September 11, 2024
概括
在分娩前一周的极端温度显著增加了新生儿重症监护室 (NICU) 入院的风险. 暴露于极端的高温和低温都会增加新生儿不良后果的可能性.
科学领域:
- 环境健康 环境健康
- 新生儿健康 新生儿健康
- 流行病学 流行病学
背景情况:
- 怀孕期间的极端温度与不良分娩结果有关,如早产和低出生体重.
- 有限的研究存在于极端温度和新生儿重症监护室 (NICU) 入院之间的关联.
研究的目的:
- 调查分娩周环境温度变化与新生儿重症监护室入院风险之间的关联.
- 量化与每日和每周平均温度变化相关的NICU入院风险,包括极端的高温和低温.
主要方法:
- 采用了一个案例交叉研究设计,将安全劳动协会 (2002-2008) 的数据与环境温度数据联系起来.
- 调整的危险比率 (HR) 和95%置信区间 (CI) 为每1°C的温度变化计算了NICU入院风险.
- 分析考虑了每天和每周的平均温度,调整为PM2.5和相对湿度,并检查了极端温度百分位数.
主要成果:
- 在分娩周内温度升高1°C,与新生儿重症监护室入院风险没有关联.
- 每周平均气温下降1°C至低于第10个百分点和第5个百分点,与分别增加30%和47%的新生儿重症监护室入院风险有关.
- 超过第90和第95百分点的每周平均温度增加1°C与分别增加2倍和4倍以上的新生儿重症监护室入院风险有关.
结论:
- 在分娩前一周的极端温度与新生儿重症监护室入院的风险增加有关.
- 极端高温暴露与较高的NICU入院率有着特别强烈的关联.
- 这些发现强调了由于持续的极端温度而导致新生儿不良后果的可能性.
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