通过饮食和补充剂评估通过饮食和补充剂对老年人痴呆风险认知功能的影响:随机对照试验的协议
Vinicius do Rosario1, Elnaz Lorzadeh1, Henry Brodaty2
1School of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.
BMJ open
|September 11, 2024
概括
这项研究调查了紫色食物或黑补充剂中的安托西亚宁是否可以预防老年人的记忆力丧失. 结果将为认知和心血管健康的饮食策略提供信息.
科学领域:
- 营养神经科学 营养神经科学
- 老年学是一门学科.
- 心血管健康 心血管健康
背景情况:
- 饮食中含有的黄类化合物,特别是酸,显示出潜在的认知,抗炎和神经保护作用.
- 患痴呆症风险较高的老年人经常经历记忆力下降和炎症.
研究的目的:
- 为了确定通过饮食或补充剂消费的安托西亚尼能否预防高危老年人记忆丧失的进展.
- 评估安东基氨酸对炎症和心血管标志物的影响.
主要方法:
- 一项为期6个月的多中心随机对照试验,涉及60-85岁的轻度认知障碍或记忆障碍的成年人.
- 参与者被分配到高素 ("紫色食物") 饮食,黑补充剂或对照组.
- 主要结局:听觉前级记忆;次要结局:认知功能,血压,炎症生物标志物和肠道微生物群.
主要成果:
- 数据收集和分析正在进行中.
- 目前没有结果可用.
结论:
- 预计这项研究将提供有关安东素在支持老年人群认知和心血管健康方面的有效性证据.
- 调查结果将为关于预防痴呆症的饮食干预措施的公共卫生建议提供信息.
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