性饮食对成年人脂质代谢的影响:系统审查协议
Serene Hilary1, Linda Östlundh2, Carine Platat3
1Department of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE.
BMJ open
|September 11, 2024
概括
饮食对成年人的脂质代谢有不同的影响,对胆固醇和甘油三酸有不同的影响. 这次系统审查将总结有关其心脏代谢风险的发现.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 低碳水化合物摄入量极低的类饮食是减肥和改善高血糖的公认方法.
- 基因饮食中脂肪消耗增加引发了人们对成人心脏代谢风险的担忧.
- 现有研究表明,性饮食对脂质代谢的影响不一致,一些研究报告改善,而另一些研究表明低密度脂蛋白 (LDL) 和甘油三酸的增加.
研究的目的:
- 系统地审查和总结基因饮食干预措施对成年人群脂质代谢的影响.
- 评估与饮食相关的潜在心脏代谢风险.
- 提供基于证据的信息,以帮助公众了解质饮食对脂质资料的影响.
主要方法:
- 在五个主要数据库中进行系统的文献搜索:PubMed,Embase,Scopus,Cochrane图书馆和Web of Science.
- 将包括涉及成人饮食干预措施的研究,但不包括被诊断患有神经系统疾病的人群.
- 将使用随机效应元分析提取和分析数据,以确定总胆固醇,LDL和甘油三度变化的综合估计,并进行子组分析以探索异质性.
主要成果:
- 本节不适用,因为这是系统审查的协议,而不是审查本身.
- 系统审查将综合符合条件的研究中的定量数据.
- 聚合估计将表明性饮食对关键脂质参数的整体影响.
结论:
- 系统性审查将阐明性饮食对脂肪代谢和成人相关心脏代谢风险的影响.
- 调查结果将为公众健康指导和关于采用素饮食的临床建议提供信息.
- 结果将通过发表在同行评审期刊中进行传播.
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