三甘油糖指数与牛皮患者全因死亡率之间的关联
Yanqian Su1, Huijuan Shi1,2, Jue Tang1
1Department of Dermatology, Beijing Chao-yang Hospital, Capital Medical University.
The Tohoku journal of experimental medicine
|September 11, 2024
概括
甘油三糖 (TyG) 指数与牛皮患者全因死亡风险增加有关. 较高的TyG指数水平表明这个人群中死亡风险更高.
科学领域:
- 心血管健康 心血管健康
- 皮肤病学 皮肤病学
- 代谢综合征是代谢综合征的一种.
背景情况:
- 三甘油糖 (TyG) 指数是胰岛素抵抗和心血管风险的新兴标志物.
- 虽然TyG指数与死亡率有关,但它在牛皮患者中的具体作用尚未明确.
研究的目的:
- 研究三糖糖 (TyG) 指数与牛皮患者全因死亡率之间的关联.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 采用加权多变量考克斯回归和限制立方线 (RCS) 模型来分析TyG指数 (连续和三位数) 和死亡风险.
- 进行了卡普兰-梅尔 (KM) 存活曲线和灵敏度/子组分析.
主要成果:
- 死亡的牛皮患者与幸存者相比,TyG指数值显著更高.
- 在完全调整后,发现TyG指数与全因死亡风险 (HR1.78,P=0.012) 之间存在正相关性.
- 与TyG指数最高三分之一的参与者相比,与最低三分之一的参与者相比,所有原因死亡率的风险大幅增加 (HR3.05,P=0.027).
结论:
- 三甘油糖 (TyG) 指数与牛皮患者的全因死亡风险正相关.
- 泰格指数可以作为一种有价值的预测标志物来预测牛皮患者的长期死亡率.
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