在决策过程中将感觉与行动联系起来的全大脑动态
Andrei Khilkevich1, Michael Lohse2, Ryan Low3
1Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK. a.khilkevich@ucl.ac.uk.
Nature
|September 11, 2024
概括
学习改变了整个大脑的神经活动, 证据的整合和行动准备在许多大脑区域之间保持一致,从而实现并行的感觉运动转换.
科学领域:
- 神经科学
- 认知科学
- 计算神经科学
背景情况:
- 感知决策通过证据整合将感官输入与行动联系起来.
- 通过大脑区域进行感官处理,证据积累和运动控制的编排仍然不太清楚.
研究的目的:
- 在决策过程中研究大脑神经活动如何调节从感官输入到行动执行的转变.
- 在学习感知决策过程中绘制大脑区域信息的流动.
主要方法:
- 在执行视觉证据报告任务的小鼠中记录整个大脑的神经活动.
- 分析了与证据整合,运动准备和执行有关的神经群体动态.
主要成果:
- 在大脑的广泛区域出现了证据整合, 推动运动准备活动.
- 视觉信息从短暂的感官反应转变为支持并行证据积累的持续表示.
- 分享人口活动编码证据和移动准备,与移动执行不同.
- 证据整合时间表取决于任务经验,而不是大脑区域的内在特征.
结论:
- 在许多大脑区域中,学习使证据的积累与行动的准备相一致.
- 决策涉及高度分布和并行传感运动转换.
- 为了解感官证据如何指导行为,提出了一个大脑范围的框架.
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