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Updated: Jun 13, 2025

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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在对蛋白质体功能障碍的反应中,CaMKII通过酸化BAG3来抑制蛋白质毒性

Chenliang Zhang1, Huanji Xu2, Qiulin Tang1

  • 1Division of Abdominal Tumor Multimodality Treatment, Department of Medical Oncology, Cancer Center and Laboratory of Molecular Targeted Therapy in Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.

EMBO reports
|September 11, 2024
PubMed
概括

/卡尔莫杜林依赖蛋白激酶II (CaMKII) 通过化BAG3,抑制蛋白质合成和减轻蛋白质毒性,在蛋白质酶抑制期间维持蛋白质稳定. 这揭示了蛋白酶体抑制剂治疗的新质量控制机制和治疗策略.

关键词:
BAG3 BAG3 BAG3 BAG3 BAG3 BAG3 BAG3 BAG3 BAG3卡姆基尔是什么意思 卡姆基尔在HRI上,HRI是HRI.帕拉普托西斯 (Paraptosis) 是一种蛋白质酶抑制是一种蛋白质酶抑制.

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