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Updated: Jun 13, 2025

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
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双对应染色体适应了幸存者和BRG1/SWI复合体,以激活CD4+细胞中的DNA损伤反应

Venkataragavan Chandrasekaran1, Karin M E Andersson1, Malin Erlandsson1,2

  • 1Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 480, Gothenburg, 40530, Sweden.

Cell communication and signaling : CCS
|September 11, 2024
PubMed
概括

双对应色素区域 (BvCR) 控制CD4+细胞中的DNA损伤反应. 幸存者蛋白质将染色体重塑复合体在BvCR上,抑制DNA修复,为类风湿性关节炎等自身免疫性疾病提供治疗点.

关键词:
这是一种自身免疫力.这就是BRG1的原因.双对应的染色质二元素造成的DNA损伤是DNA损伤.幸存下来就是生存.

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