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Updated: Jun 13, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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在开发A类GPCR偏差联体的进展

Paula Morales1, Magdalena M Scharf2, Marcel Bermudez3

  • 1Instituto de Química Médica, Consejo Superior de Investigaciones Científicas, Madrid, Spain.

British journal of pharmacology
|September 11, 2024
PubMed
概括

在G蛋白合受体 (GPCRs) 中偏差信号提供了新的治疗潜力. 功能选择性连接体向特定的途径,为未开发的GPCR寻找更安全,更有效的药物.

关键词:
与G蛋白结合的受体.的GPCR调制器.有偏见的信号传输.具有功能选择性的带.

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