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通过维持线粒体平衡,LONP1可以缓解与衰老相关的纤维化

Congxiao Zhang1, Siman Shen2, Li Xu3

  • 1Blood Purification Center, The Fourth People's Hospital of Shenyang, China Medical University, Shenyang, Liaoning, P. R. China.

Journal of cellular and molecular medicine
|September 11, 2024
PubMed
概括

衰老中的Lon蛋白酶1 (LONP1) 减少会使纤维化和线粒体问题恶化. 恢复LONP1可以缓解这些问题,这表明LONP1是与年龄相关的脏疾病的治疗标.

关键词:
这就是LONP1的意义.年龄化的衰老.m6A 甲基转移酶 METTL3 的作用.线粒体的恒常状态是线粒体的恒常状态脏纤维化 脏纤维化

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