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PNPLA3 I148M的性别特异性影响

Alessandro Cherubini1, Chiara Rosso2, Sara Della Torre3

  • 1Department of Transfusion Medicine, Precision Medicine-Biological Resource Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Liver international : official journal of the International Association for the Study of the Liver
|September 12, 2024
PubMed
概括

与代谢功能障碍相关的脂肪性肝病 (MASLD) 影响男性的比例高于女性,但PNPLA3 I148M变异对女性构成特别的风险. 研究正在探索这种在MASLD发育中的性别特异性作用背后的分子机制.

关键词:
肝细胞癌 (HCC) 是一种肝细胞癌.人类肝脏有机体代谢功能障碍相关脂肪性肝病 (MASLD)性二重形性质性质二重形性质.

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