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Updated: Jun 13, 2025

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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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动脉硬与新发慢性病相关
1Department of Internal Medicine, Wenfeng District Xiguan Subdistrict Office Community Health Center, Anyang, China.
VASA. Zeitschrift fur Gefasskrankheiten
|September 12, 2024
概括
动脉硬度,以腕脉冲波速度 (baPWV) 衡量,与发展新发性慢性病 (CKD) 密切相关. 较高的baPWV表明患CKD的风险增加.
科学领域:
- 心血管医学 心血管医学
- 腎臟病學 (nephrology) 是一種醫學.
- 流行病学 流行病学
背景情况:
- 动脉硬与新发慢性病 (CKD) 之间的独立关联需要进一步调查.
- 动脉硬度 (AS) 是心血管事件的已知危险因素,可能影响脏健康.
研究的目的:
- 为了检查动脉硬度之间的关系,用手腕脚脉冲波速度 (baPWV) 来量化,以及新发性CKD的发病率.
- 确定baPWV是否是CKD发展的独立预测因素.
主要方法:
- 一项前性队列研究,涉及Kailuan研究中的6929名参与者,所有参与者在基线时都没有CKD.
- 根据baPWV水平,参与者被分为四组.
- 考克斯回归模型被用来评估baPWV与新发性CKD风险之间的关联,在10.06年的随访期内.
主要成果:
- 在随访期间,共发现962例新发性CKD病例.
- 考克斯的比例危险分析显示,高baPWV四分位数与患CKD风险增加之间存在显著的正相关性.
- 在对潜在混因素进行调整后,这种关联仍然显著.
结论:
- 腕脉冲波速度 (baPWV) 是新发慢性病 (CKD) 的重要预测因素.
- 较高的baPWV表明动脉硬度升高,与患CKD的风险增加有关.
- baPWV可以作为一种有价值的临床标志物,用于识别患有新发性CKD风险的个体.
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